ctcRbase

Entry Detail

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General Information

Database ID: SKCM04249 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MAF Full Name: MAF bZIP transcription factor Category: mRNA Synonyms: AYGRP|CCA4|CTRCT21|c-MAF Chromosome: chr16 Strand: - Coordinate: Start Site(bp): 79585843 End Site(bp): 79600714 Gene Summary: The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010] External Links: Ensembl ID: ENSG00000178573 HGNC ID: HGNC:6776 Entrez Gene: 4094

Expression Profile of MAF Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-130a-3p YES NO YES hsa-miR-130b-3p YES NO YES hsa-miR-143-3p YES YES YES hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-151a-3p YES NO YES hsa-miR-152-3p YES YES YES hsa-miR-154-5p YES YES YES hsa-miR-301a-3p YES NO YES hsa-miR-301b-3p YES NO YES hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-330-3p YES NO YES hsa-miR-338-3p YES YES YES hsa-miR-454-3p YES NO YES hsa-miR-455-3p YES NO YES Display: