ctcRbase

Entry Detail

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General Information

Database ID: SKCM04251 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CNST Full Name: consortin, connexin sorting protein Category: mRNA Synonyms: C1orf71|PPP1R64 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 246566444 End Site(bp): 246668584 Gene Summary: Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]).[supplied by OMIM, Jun 2010] External Links: Ensembl ID: ENSG00000162852 HGNC ID: HGNC:26486 Entrez Gene: 163882

Expression Profile of CNST Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-374a-5p NO YES YES hsa-miR-374b-5p NO YES YES hsa-miR-425-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-499a-5p YES YES NO hsa-miR-9-5p YES YES NO Display: