ctcRbase

Entry Detail

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General Information

Database ID: SKCM04332 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SMARCE1 Full Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 Category: mRNA Synonyms: BAF57|CSS5 Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 40624962 End Site(bp): 40648508 Gene Summary: The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000073584 HGNC ID: HGNC:11109 Entrez Gene: 6605

Expression Profile of SMARCE1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-1297 YES YES NO hsa-miR-134-5p YES YES NO hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-199a-5p NO YES YES hsa-miR-199b-5p NO YES YES hsa-miR-21-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-320a YES NO YES hsa-miR-320b YES NO YES hsa-miR-320c YES NO YES hsa-miR-320d YES NO YES hsa-miR-335-5p NO YES YES hsa-miR-381-3p YES YES NO hsa-miR-383-5p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-485-5p YES NO YES hsa-miR-490-3p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-590-5p YES YES NO hsa-miR-615-3p NO YES YES hsa-miR-655-3p YES NO YES hsa-miR-760 YES NO YES hsa-miR-876-5p NO YES YES hsa-miR-9-5p YES YES YES Display: