ctcRbase

Entry Detail

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General Information

Database ID: SKCM04370 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DUS2 Full Name: dihydrouridine synthase 2 Category: mRNA Synonyms: DUS2L|SMM1|URLC8 Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 67987746 End Site(bp): 68079320 Gene Summary: This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012] External Links: Ensembl ID: ENSG00000167264 HGNC ID: HGNC:26014 Entrez Gene: 54920

Expression Profile of DUS2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-137 YES NO YES hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-25-3p YES YES YES hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-32-5p YES YES YES hsa-miR-339-5p YES YES NO hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: