ctcRbase

Entry Detail

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General Information

Database ID: SKCM04377 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CUL4B Full Name: cullin 4B Category: mRNA Synonyms: CUL-4B|MRXHF2|MRXS15|MRXSC|SFM2 Chromosome: chrX Strand: - Coordinate: Start Site(bp): 120524609 End Site(bp): 120575794 Gene Summary: This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000158290 HGNC ID: HGNC:2555 Entrez Gene: 8450

Expression Profile of CUL4B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-141-3p YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-144-3p YES YES YES hsa-miR-146a-5p YES YES NO hsa-miR-146b-5p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-188-5p YES NO YES hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-194-5p YES YES YES hsa-miR-199a-5p YES YES NO hsa-miR-199b-5p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-204-5p YES YES YES hsa-miR-211-5p YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-217 YES YES YES hsa-miR-224-5p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-338-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-425-5p YES YES YES hsa-miR-431-5p YES YES NO hsa-miR-448 YES YES NO hsa-miR-487a-3p YES NO YES hsa-miR-488-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-653-5p YES YES NO hsa-miR-708-5p YES YES NO hsa-miR-9-5p YES YES NO Display: