ctcRbase

Entry Detail

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General Information

Database ID: SKCM04380 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ORAI1 Full Name: ORAI calcium release-activated calcium modulator 1 Category: mRNA Synonyms: CRACM1|IMD9|ORAT1|TAM2|TMEM142A Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 121626550 End Site(bp): 121642677 Gene Summary: The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011] External Links: Ensembl ID: ENSG00000276045 HGNC ID: HGNC:25896 Entrez Gene: 84876

Expression Profile of ORAI1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-17-5p YES YES YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-377-3p YES YES YES hsa-miR-454-3p YES YES NO hsa-miR-485-5p YES NO YES hsa-miR-519d-3p YES YES YES hsa-miR-7-5p YES NO YES hsa-miR-877-5p YES NO YES hsa-miR-93-5p YES YES YES Display: