Entry Detail



General Information

Database ID:SKCM04438
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:GFM1
Full Name:G elongation factor mitochondrial 1
Category:mRNA
Synonyms:COXPD1|EFG|EFG1|EFGM|EGF1|GFM|hEFG1|mtEF-G1
Chromosome:chr3
Strand:+
Coordinate:
Start Site(bp):158644278End Site(bp):158692575
Gene Summary:Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000168827
HGNC ID:HGNC:13780
Entrez Gene:85476



Expression Profile of GFM1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-181a-5p
YES
YES
NO
hsa-miR-181b-5p
YES
YES
NO
hsa-miR-181c-5p
YES
YES
NO
hsa-miR-181d-5p
YES
YES
NO
hsa-miR-204-5p
YES
YES
NO
hsa-miR-205-5p
YES
YES
NO
hsa-miR-211-5p
YES
YES
NO
hsa-miR-216a-5p
YES
YES
NO
hsa-miR-223-3p
YES
YES
NO
hsa-miR-24-3p
YES
YES
NO
hsa-miR-27a-3p
NO
YES
NO
hsa-miR-27b-3p
NO
YES
NO
hsa-miR-300
YES
YES
NO
hsa-miR-33a-5p
YES
YES
NO
hsa-miR-33b-5p
YES
YES
NO
hsa-miR-376c-3p
YES
YES
NO
hsa-miR-381-3p
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-421
YES
YES
NO
hsa-miR-425-5p
YES
YES
NO
hsa-miR-433-3p
YES
YES
NO
hsa-miR-653-5p
YES
YES
NO
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