Entry Detail



General Information

Database ID:SKCM04443
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:FRMD4A
Full Name:FERM domain containing 4A
Category:mRNA
Synonyms:CCAFCA|FRMD4|bA295P9.4
Chromosome:chr10
Strand:-
Coordinate:
Start Site(bp):13643706End Site(bp):14462142
Gene Summary:This gene encodes a FERM domain-containing protein that regulates epithelial cell polarity. It connects ADP ribosylation factor 6 (ARF6) with the Par protein complex, which regulates the remodeling of adherens junctions and linear actin cable formation during epithelial cell polarization. Polymorphisms in this gene are associated with Alzheimer's disease, and also with nicotine dependence. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
External Links:
Ensembl ID:ENSG00000151474
HGNC ID:HGNC:25491
Entrez Gene:55691



Expression Profile of FRMD4A Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-106a-5p
YES
YES
YES
hsa-miR-106b-5p
YES
YES
YES
hsa-miR-124-3p
YES
NO
YES
hsa-miR-128-3p
YES
NO
YES
hsa-miR-138-5p
YES
NO
YES
hsa-miR-139-5p
YES
YES
YES
hsa-miR-17-5p
YES
YES
YES
hsa-miR-19a-3p
YES
YES
NO
hsa-miR-19b-3p
YES
YES
NO
hsa-miR-20a-5p
YES
YES
YES
hsa-miR-20b-5p
YES
YES
YES
hsa-miR-223-3p
YES
YES
YES
hsa-miR-29a-3p
YES
NO
YES
hsa-miR-29b-3p
YES
NO
YES
hsa-miR-29c-3p
YES
NO
YES
hsa-miR-302a-3p
YES
YES
YES
hsa-miR-302b-3p
YES
YES
YES
hsa-miR-302c-3p
YES
YES
YES
hsa-miR-302d-3p
YES
YES
YES
hsa-miR-302e
YES
YES
YES
hsa-miR-34a-5p
YES
YES
YES
hsa-miR-34c-5p
YES
YES
YES
hsa-miR-372-3p
YES
YES
YES
hsa-miR-373-3p
YES
YES
YES
hsa-miR-449a
YES
YES
YES
hsa-miR-449b-5p
YES
YES
YES
hsa-miR-489-3p
YES
NO
YES
hsa-miR-506-3p
YES
NO
YES
hsa-miR-519d-3p
YES
YES
YES
hsa-miR-520a-3p
YES
YES
YES
hsa-miR-520b
YES
YES
YES
hsa-miR-520c-3p
YES
YES
YES
hsa-miR-520d-3p
YES
YES
YES
hsa-miR-520e
YES
YES
YES
hsa-miR-582-5p
YES
NO
YES
hsa-miR-802
YES
NO
YES
hsa-miR-93-5p
YES
YES
YES
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