Entry Detail



General Information

Database ID:SKCM04461
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:ATP7A
Full Name:ATPase copper transporting alpha
Category:mRNA
Synonyms:DSMAX|MK|MNK|SMAX3
Chromosome:chrX
Strand:+
Coordinate:
Start Site(bp):77910656End Site(bp):78050395
Gene Summary:This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed. [provided by RefSeq, Aug 2013]
External Links:
Ensembl ID:ENSG00000165240
HGNC ID:HGNC:869
Entrez Gene:538



Expression Profile of ATP7A Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
NO
YES
YES
hsa-miR-128-3p
YES
YES
NO
hsa-miR-154-5p
YES
YES
NO
hsa-miR-15a-5p
YES
YES
YES
hsa-miR-15b-5p
YES
YES
YES
hsa-miR-16-5p
YES
YES
YES
hsa-miR-195-5p
YES
YES
YES
hsa-miR-199a-5p
YES
YES
NO
hsa-miR-199b-5p
YES
YES
NO
hsa-miR-216b-5p
YES
YES
NO
hsa-miR-25-3p
NO
YES
YES
hsa-miR-32-5p
NO
YES
YES
hsa-miR-329-3p
YES
YES
NO
hsa-miR-340-5p
NO
YES
YES
hsa-miR-362-3p
YES
YES
NO
hsa-miR-363-3p
NO
YES
YES
hsa-miR-367-3p
NO
YES
YES
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-374b-5p
YES
YES
NO
hsa-miR-424-5p
YES
YES
YES
hsa-miR-425-5p
YES
YES
NO
hsa-miR-448
YES
YES
NO
hsa-miR-495-3p
NO
YES
YES
hsa-miR-497-5p
YES
YES
YES
hsa-miR-520f-3p
YES
NO
YES
hsa-miR-92a-3p
NO
YES
YES
hsa-miR-92b-3p
NO
YES
YES
hsa-miR-9-5p
YES
NO
YES
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