ctcRbase

Entry Detail

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General Information

Database ID: SKCM04463 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DHX29 Full Name: DExH-box helicase 29 Category: mRNA Synonyms: DDX29 Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 55256245 End Site(bp): 55307722 Gene Summary: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein functions in translation initiation, and is specifically required for ribosomal scanning across stable mRNA secondary structures during initiation codon selection. This protein may also play a role in sensing virally derived cytosolic nucleic acids. Knockdown of this gene results in reduced protein translation and impaired proliferation of cancer cells. [provided by RefSeq, Sep 2016] External Links: Ensembl ID: ENSG00000067248 HGNC ID: HGNC:15815 Entrez Gene: 54505

Expression Profile of DHX29 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-142-3p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-218-5p YES YES YES hsa-miR-429 YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-455-5p YES YES NO Display: