ctcRbase

Entry Detail

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General Information

Database ID: SKCM04481 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ARID1A Full Name: AT-rich interaction domain 1A Category: mRNA Synonyms: B120|BAF250|BAF250a|BM029|C1orf4|CSS2|ELD|MRD14|OSA1|P270|SMARCF1|hELD|hOSA1 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 26693236 End Site(bp): 26782104 Gene Summary: This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000117713 HGNC ID: HGNC:11110 Entrez Gene: 8289

Expression Profile of ARID1A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES NO YES hsa-miR-1297 YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-142-5p YES NO YES hsa-miR-144-3p YES NO YES hsa-miR-153-3p YES YES YES hsa-miR-185-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-19a-3p YES NO YES hsa-miR-19b-3p YES NO YES hsa-miR-205-5p YES YES YES hsa-miR-212-3p YES YES NO hsa-miR-216a-5p YES YES YES hsa-miR-216b-5p YES YES YES hsa-miR-217 YES NO YES hsa-miR-221-3p YES YES YES hsa-miR-222-3p YES YES YES hsa-miR-223-3p YES YES YES hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-30a-5p YES YES YES hsa-miR-30b-5p YES YES YES hsa-miR-30c-5p YES YES YES hsa-miR-30d-5p YES YES YES hsa-miR-30e-5p YES YES YES hsa-miR-31-5p YES YES YES hsa-miR-324-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-382-5p YES YES NO hsa-miR-448 YES YES NO hsa-miR-455-5p YES YES YES hsa-miR-486-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-582-5p YES NO NO hsa-miR-599 YES YES NO hsa-miR-625-5p YES NO NO hsa-miR-653-5p YES YES NO hsa-miR-802 YES NO YES hsa-miR-9-5p YES YES YES Display: