Entry Detail



General Information

Database ID:SKCM04502
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:EYA3
Full Name:EYA transcriptional coactivator and phosphatase 3
Category:mRNA
Synonyms:-
Chromosome:chr1
Strand:-
Coordinate:
Start Site(bp):27970344End Site(bp):28088696
Gene Summary:This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]
External Links:
Ensembl ID:ENSG00000158161
HGNC ID:HGNC:3521
Entrez Gene:2140



Expression Profile of EYA3 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-28-5p
YES
YES
YES
hsa-miR-708-5p
YES
YES
YES
Display: