ctcRbase

Entry Detail

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General Information

Database ID: SKCM04510 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: AKT2 Full Name: AKT serine/threonine kinase 2 Category: mRNA Synonyms: HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA Chromosome: chr19 Strand: - Coordinate: Start Site(bp): 40230317 End Site(bp): 40285536 Gene Summary: This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000105221 HGNC ID: HGNC:392 Entrez Gene: 208

Expression Profile of AKT2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-124-3p YES NO YES hsa-miR-137 YES YES YES hsa-miR-194-5p YES NO YES hsa-miR-200b-3p YES NO YES hsa-miR-200c-3p YES NO YES hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-29a-3p YES YES NO hsa-miR-29b-3p YES YES NO hsa-miR-29c-3p YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-342-3p YES NO YES hsa-miR-377-3p YES NO YES hsa-miR-429 YES NO YES hsa-miR-506-3p YES NO YES hsa-miR-625-5p YES NO NO hsa-miR-98-5p YES YES YES Display: