ctcRbase

Entry Detail

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General Information

Database ID: SKCM04528 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DDX20 Full Name: DEAD-box helicase 20 Category: mRNA Synonyms: DP103|GEMIN3 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 111755245 End Site(bp): 111768016 Gene Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000064703 HGNC ID: HGNC:2743 Entrez Gene: 11218

Expression Profile of DDX20 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-137 YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-421 YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-875-5p YES YES NO Display: