Entry Detail



General Information

Database ID:SKCM04539
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:IFT74
Full Name:intraflagellar transport 74
Category:mRNA
Synonyms:BBS20|CCDC2|CMG-1|CMG1
Chromosome:chr9
Strand:+
Coordinate:
Start Site(bp):26947039End Site(bp):27062930
Gene Summary:This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome. [provided by RefSeq, Mar 2017]
External Links:
Ensembl ID:ENSG00000096872
HGNC ID:HGNC:21424
Entrez Gene:80173



Expression Profile of IFT74 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-129-5p
YES
YES
NO
hsa-miR-141-3p
YES
YES
NO
hsa-miR-15a-5p
YES
YES
NO
hsa-miR-15b-5p
YES
YES
NO
hsa-miR-16-5p
YES
YES
NO
hsa-miR-181a-5p
YES
YES
NO
hsa-miR-181b-5p
YES
YES
NO
hsa-miR-181c-5p
YES
YES
NO
hsa-miR-181d-5p
YES
YES
NO
hsa-miR-195-5p
YES
YES
NO
hsa-miR-200a-3p
YES
YES
NO
hsa-miR-30a-5p
YES
YES
NO
hsa-miR-30b-5p
YES
YES
NO
hsa-miR-30c-5p
YES
YES
NO
hsa-miR-30d-5p
YES
YES
NO
hsa-miR-30e-5p
YES
YES
NO
hsa-miR-371a-5p
YES
YES
NO
hsa-miR-424-5p
YES
YES
NO
hsa-miR-497-5p
YES
YES
NO
hsa-miR-543
YES
YES
NO
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