ctcRbase

Entry Detail

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General Information

Database ID: SKCM04554 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ELP1 Full Name: elongator complex protein 1 Category: mRNA Synonyms: DYS|FD|IKAP|IKBKAP|IKI3|TOT1 Chromosome: chr9 Strand: - Coordinate: Start Site(bp): 108867517 End Site(bp): 108934116 Gene Summary: The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] External Links: Ensembl ID: ENSG00000070061 HGNC ID: HGNC:5959 Entrez Gene: 8518

Expression Profile of ELP1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-1251-5p YES NO YES hsa-miR-132-3p YES YES NO hsa-miR-145-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-371a-5p YES YES YES hsa-miR-377-3p YES YES NO hsa-miR-431-5p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-98-5p YES YES YES Display: