ctcRbase

Entry Detail

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General Information

Database ID: SKCM04611 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: EME1 Full Name: essential meiotic structure-specific endonuclease 1 Category: mRNA Synonyms: MMS4L|SLX2A Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 50373220 End Site(bp): 50381483 Gene Summary: This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009] External Links: Ensembl ID: ENSG00000154920 HGNC ID: HGNC:24965 Entrez Gene: 146956

Expression Profile of EME1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-876-5p YES YES YES Display: