Entry Detail



General Information

Database ID:SKCM04613
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:FBXO17
Full Name:F-box protein 17
Category:mRNA
Synonyms:FBG4|FBX26|FBXO26|Fbx17
Chromosome:chr19
Strand:-
Coordinate:
Start Site(bp):38941401End Site(bp):38975910
Gene Summary:This gene encodes a member of the F-box protein family which is characterized by the F-box motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
External Links:
Ensembl ID:ENSG00000269190
HGNC ID:HGNC:18754
Entrez Gene:115290



Expression Profile of FBXO17 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-128-3p
YES
YES
NO
hsa-miR-134-5p
YES
YES
NO
hsa-miR-27a-3p
YES
YES
NO
hsa-miR-27b-3p
YES
YES
NO
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-377-3p
YES
YES
NO
hsa-miR-431-5p
YES
YES
NO
hsa-miR-758-3p
YES
YES
NO
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