ctcRbase

Entry Detail

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General Information

Database ID: SKCM04616 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: DYNC2LI1 Full Name: dynein cytoplasmic 2 light intermediate chain 1 Category: mRNA Synonyms: CGI-60|D2LIC|LIC3 Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 43774039 End Site(bp): 43810010 Gene Summary: This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017] External Links: Ensembl ID: ENSG00000138036 HGNC ID: HGNC:24595 Entrez Gene: 51626

Expression Profile of DYNC2LI1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-128-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-27a-3p YES YES NO hsa-miR-27b-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-495-3p YES YES NO Display: