Entry Detail



General Information

Database ID:SKCM04624
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:CHD8
Full Name:chromodomain helicase DNA binding protein 8
Category:mRNA
Synonyms:AUTS18|HELSNF1
Chromosome:chr14
Strand:-
Coordinate:
Start Site(bp):21385194End Site(bp):21456126
Gene Summary:This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahma and kismet domains, which are common to the subfamily of chromodomain-helicase-DNA binding proteins to which this protein belongs. This gene has been shown to function in several processes that include transcriptional regulation, epigenetic remodeling, promotion of cell proliferation, and regulation of RNA synthesis. Allelic variants of this gene are associated with autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016]
External Links:
Ensembl ID:ENSG00000100888
HGNC ID:HGNC:20153
Entrez Gene:57680



Expression Profile of CHD8 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-132-3p
YES
NO
YES
hsa-miR-140-5p
YES
YES
NO
hsa-miR-155-5p
YES
YES
YES
hsa-miR-15a-5p
YES
YES
NO
hsa-miR-15b-5p
YES
YES
NO
hsa-miR-16-5p
YES
YES
NO
hsa-miR-194-5p
YES
YES
YES
hsa-miR-195-5p
YES
YES
NO
hsa-miR-212-3p
YES
NO
YES
hsa-miR-221-3p
YES
YES
YES
hsa-miR-222-3p
YES
YES
YES
hsa-miR-365a-3p
YES
YES
YES
hsa-miR-424-5p
YES
YES
NO
hsa-miR-497-5p
YES
YES
NO
hsa-miR-503-5p
YES
YES
NO
hsa-miR-760
YES
NO
YES
hsa-miR-873-5p
YES
YES
YES
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