ctcRbase

Entry Detail

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General Information

Database ID: SKCM04655 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: GABPA Full Name: GA binding protein transcription factor subunit alpha Category: mRNA Synonyms: E4TF1-60|E4TF1A|NFT2|NRF2|NRF2A|RCH04A07 Chromosome: chr21 Strand: + Coordinate: Start Site(bp): 25734570 End Site(bp): 25772460 Gene Summary: This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010] External Links: Ensembl ID: ENSG00000154727 HGNC ID: HGNC:4071 Entrez Gene: 2551

Expression Profile of GABPA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES NO YES hsa-let-7b-5p YES NO YES hsa-let-7c-5p YES NO YES hsa-let-7d-5p YES NO YES hsa-let-7e-5p YES NO YES hsa-let-7f-5p YES NO YES hsa-let-7g-5p YES NO YES hsa-let-7i-5p YES NO YES hsa-miR-153-3p YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-193a-3p YES YES NO hsa-miR-195-5p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-205-5p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-371a-5p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-429 YES YES YES hsa-miR-452-5p YES NO YES hsa-miR-488-3p YES YES YES hsa-miR-490-3p YES YES YES hsa-miR-495-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-655-3p YES NO YES hsa-miR-98-5p YES NO YES Display: