ctcRbase

Entry Detail

---



General Information

Database ID: SKCM04671 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SLC39A14 Full Name: solute carrier family 39 member 14 Category: mRNA Synonyms: HCIN|HMNDYT2|LZT-Hs4|NET34|ZIP14|cig19 Chromosome: chr8 Strand: + Coordinate: Start Site(bp): 22367249 End Site(bp): 22434129 Gene Summary: This gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an important transporter of nontransferrin-bound iron and a critical regulator of manganese homeostasis. Naturally occurring mutations in this gene are associated with neurodegeneration with brain iron accumulation and early-onset parkinsonism-dystonia with hypermanganesemia. [provided by RefSeq, May 2017] External Links: Ensembl ID: ENSG00000104635 HGNC ID: HGNC:20858 Entrez Gene: 23516

Expression Profile of SLC39A14 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-185-5p YES YES YES hsa-miR-186-5p YES YES YES hsa-miR-200b-3p YES YES YES hsa-miR-200c-3p YES YES YES hsa-miR-204-5p YES NO YES hsa-miR-211-5p YES NO YES hsa-miR-216a-5p YES YES NO hsa-miR-218-5p YES YES YES hsa-miR-223-3p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-331-3p YES NO YES hsa-miR-338-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-429 YES YES YES hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-451a YES YES NO hsa-miR-455-3p YES NO YES hsa-miR-490-3p YES YES YES hsa-miR-491-5p YES YES NO hsa-miR-543 YES YES NO hsa-miR-582-5p YES NO YES hsa-miR-655-3p YES NO YES hsa-miR-708-5p YES YES NO hsa-miR-9-5p YES YES YES Display: