ctcRbase

Entry Detail

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General Information

Database ID: SKCM04673 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: HMGCL Full Name: 3-hydroxy-3-methylglutaryl-CoA lyase Category: mRNA Synonyms: HL Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 23801885 End Site(bp): 23838620 Gene Summary: The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] External Links: Ensembl ID: ENSG00000117305 HGNC ID: HGNC:5005 Entrez Gene: 3155

Expression Profile of HMGCL Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-455-5p YES YES NO Display: