ctcRbase

Entry Detail

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General Information

Database ID: SKCM04705 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CYFIP1 Full Name: cytoplasmic FMR1 interacting protein 1 Category: mRNA Synonyms: P140SRA-1|SHYC|SRA-1|SRA1 Chromosome: chr15 Strand: - Coordinate: Start Site(bp): 22867052 End Site(bp): 22981063 Gene Summary: This gene encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization.This protein also interacts with the Fragile X mental retardation protein (FMRP) and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion. [provided by RefSeq, May 2017] External Links: Ensembl ID: ENSG00000273749 HGNC ID: HGNC:13759 Entrez Gene: 23191

Expression Profile of CYFIP1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-214-3p YES YES NO hsa-miR-216a-5p YES YES YES hsa-miR-216b-5p YES NO YES hsa-miR-22-3p YES YES NO hsa-miR-224-5p YES YES YES hsa-miR-300 YES YES YES hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES YES hsa-miR-381-3p YES YES YES hsa-miR-424-5p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-503-5p YES YES NO Display: