Entry Detail



General Information

Database ID:SKCM04717
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:KCNS3
Full Name:potassium voltage-gated channel modifier subfamily S member 3
Category:mRNA
Synonyms:KV9.3
Chromosome:chr2
Strand:+
Coordinate:
Start Site(bp):17877847End Site(bp):18361616
Gene Summary:Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013]
External Links:
Ensembl ID:ENSG00000170745
HGNC ID:HGNC:6302
Entrez Gene:3790



Expression Profile of KCNS3 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-10a-5p
YES
YES
NO
hsa-miR-10b-5p
YES
YES
NO
hsa-miR-124-3p
YES
YES
NO
hsa-miR-125a-5p
YES
YES
YES
hsa-miR-125b-5p
YES
YES
YES
hsa-miR-135a-5p
YES
YES
YES
hsa-miR-135b-5p
YES
YES
YES
hsa-miR-192-5p
YES
YES
NO
hsa-miR-215-5p
YES
YES
NO
hsa-miR-27a-3p
YES
YES
NO
hsa-miR-27b-3p
YES
YES
NO
hsa-miR-342-3p
YES
YES
NO
hsa-miR-488-3p
YES
YES
NO
hsa-miR-506-3p
YES
YES
NO
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