ctcRbase

Entry Detail

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General Information

Database ID: SKCM04765 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: PHKG2 Full Name: phosphorylase kinase catalytic subunit gamma 2 Category: mRNA Synonyms: GSD9C Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 30748270 End Site(bp): 30761176 Gene Summary: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010] External Links: Ensembl ID: ENSG00000156873 HGNC ID: HGNC:8931 Entrez Gene: 5261

Expression Profile of PHKG2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1-3p YES NO YES hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-206 YES NO YES hsa-miR-28-5p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-613 YES NO YES hsa-miR-708-5p YES YES NO Display: