ctcRbase

Entry Detail

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General Information

Database ID: SKCM04798 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TNFAIP6 Full Name: TNF alpha induced protein 6 Category: mRNA Synonyms: TSG-6|TSG6 Chromosome: chr2 Strand: + Coordinate: Start Site(bp): 151357592 End Site(bp): 151380048 Gene Summary: The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.[provided by RefSeq, Dec 2010] External Links: Ensembl ID: ENSG00000123610 HGNC ID: HGNC:11898 Entrez Gene: 7130

Expression Profile of TNFAIP6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-132-3p YES YES NO hsa-miR-137 YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-25-3p YES YES NO hsa-miR-300 YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: