ctcRbase

Entry Detail

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General Information

Database ID: SKCM04814 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: BBS2 Full Name: Bardet-Biedl syndrome 2 Category: mRNA Synonyms: BBS|RP74 Chromosome: chr16 Strand: - Coordinate: Start Site(bp): 56466836 End Site(bp): 56520283 Gene Summary: This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and cognitive disability. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with seven other BBS proteins.[provided by RefSeq, Oct 2014] External Links: Ensembl ID: ENSG00000125124 HGNC ID: HGNC:967 Entrez Gene: 583

Expression Profile of BBS2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-154-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-338-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-873-5p YES YES NO Display: