Entry Detail



General Information

Database ID:SKCM04837
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:SH3GL1
Full Name:SH3 domain containing GRB2 like 1, endophilin A2
Category:mRNA
Synonyms:CNSA1|EEN|SH3D2B|SH3P8
Chromosome:chr19
Strand:-
Coordinate:
Start Site(bp):4360370End Site(bp):4400547
Gene Summary:This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
External Links:
Ensembl ID:ENSG00000141985
HGNC ID:HGNC:10830
Entrez Gene:6455



Expression Profile of SH3GL1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-138-5p
YES
NO
YES
hsa-miR-1-3p
YES
NO
YES
hsa-miR-184
YES
YES
NO
hsa-miR-200b-3p
YES
NO
YES
hsa-miR-200c-3p
YES
NO
YES
hsa-miR-206
YES
NO
YES
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-33a-5p
YES
YES
NO
hsa-miR-33b-5p
YES
YES
NO
hsa-miR-429
YES
NO
YES
hsa-miR-613
YES
NO
YES
hsa-miR-655-3p
YES
NO
YES
hsa-miR-874-3p
YES
YES
NO
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