Entry Detail



General Information

Database ID:SKCM04878
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:SPATA5
Full Name:spermatogenesis associated 5
Category:mRNA
Synonyms:AFG2|EHLMRS|SPAF
Chromosome:chr4
Strand:+
Coordinate:
Start Site(bp):122923074End Site(bp):123319450
Gene Summary:This gene encodes a member of the ATPase associated with diverse activities family, whose members are defined by a highly conserved ATPase domain. Members of this family participate in diverse cellular processes that include membrane fusion, DNA replication, microtubule severing, and protein degradation. The protein encoded by this gene has a putative mitochondrial targeting sequence and has been proposed to function in maintenance of mitochondrial function and integrity during mouse spermatogenesis. Allelic variants in this gene have been associated with epilepsy, hearing loss, and cognitive disability syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
External Links:
Ensembl ID:ENSG00000145375
HGNC ID:HGNC:18119
Entrez Gene:166378



Expression Profile of SPATA5 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-140-5p
YES
YES
NO
hsa-miR-186-5p
YES
NO
YES
hsa-miR-190a-5p
YES
YES
NO
hsa-miR-190b
YES
YES
NO
hsa-miR-199a-5p
YES
YES
NO
hsa-miR-199b-5p
YES
YES
NO
hsa-miR-29b-3p
YES
YES
NO
hsa-miR-326
YES
YES
NO
hsa-miR-330-5p
YES
YES
NO
hsa-miR-425-5p
YES
YES
NO
hsa-miR-454-3p
YES
YES
NO
hsa-miR-494-3p
YES
YES
YES
hsa-miR-496
YES
YES
NO
hsa-miR-543
YES
YES
NO
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