ctcRbase

Entry Detail

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General Information

Database ID: SKCM04929 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MRPS30 Full Name: mitochondrial ribosomal protein S30 Category: mRNA Synonyms: MRP-S30|PAP|PDCD9|S30mt Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 44808925 End Site(bp): 44820428 Gene Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that is similar to the chicken pro-apoptotic protein p52. Transcript variants using alternative promoters or polyA sites have been mentioned in the literature but the complete description of these sequences is not available. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000112996 HGNC ID: HGNC:8769 Entrez Gene: 10884

Expression Profile of MRPS30 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-205-5p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-371a-5p YES YES YES hsa-miR-375 YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-876-5p YES YES NO Display: