ctcRbase

Entry Detail

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General Information

Database ID: SKCM04940 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ENPP2 Full Name: ectonucleotide pyrophosphatase/phosphodiesterase 2 Category: mRNA Synonyms: ATX|ATX-X|AUTOTAXIN|LysoPLD|NPP2|PD-IALPHA|PDNP2 Chromosome: chr8 Strand: - Coordinate: Start Site(bp): 119557086 End Site(bp): 119673453 Gene Summary: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008] External Links: Ensembl ID: ENSG00000136960 HGNC ID: HGNC:3357 Entrez Gene: 5168

Expression Profile of ENPP2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES YES hsa-miR-103a-3p YES YES YES hsa-miR-107 YES YES YES hsa-miR-124-3p YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-22-3p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-29a-3p YES YES YES hsa-miR-29b-3p YES YES YES hsa-miR-29c-3p YES YES YES hsa-miR-300 YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-543 YES YES NO Display: