ctcRbase

Entry Detail

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General Information

Database ID: SKCM04970 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: RNF216 Full Name: ring finger protein 216 Category: mRNA Synonyms: CAHH|TRIAD3|U7I1|UBCE7IP1|ZIN Chromosome: chr7 Strand: - Coordinate: Start Site(bp): 5620047 End Site(bp): 5781739 Gene Summary: This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000011275 HGNC ID: HGNC:21698 Entrez Gene: 54476

Expression Profile of RNF216 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-124-3p YES NO YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-145-5p YES YES YES hsa-miR-17-5p YES YES NO hsa-miR-186-5p YES NO YES hsa-miR-191-5p YES YES NO hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-19a-3p YES YES YES hsa-miR-19b-3p YES YES YES hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-28-3p YES NO YES hsa-miR-300 YES NO YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-302a-3p YES NO YES hsa-miR-302b-3p YES NO YES hsa-miR-302c-3p YES NO YES hsa-miR-302d-3p YES NO YES hsa-miR-302e YES NO YES hsa-miR-329-3p YES NO YES hsa-miR-362-3p YES NO YES hsa-miR-372-3p YES NO YES hsa-miR-373-3p YES NO YES hsa-miR-381-3p YES NO YES hsa-miR-423-5p YES NO NO hsa-miR-454-3p YES YES YES hsa-miR-520a-3p YES NO YES hsa-miR-520b YES NO YES hsa-miR-520c-3p YES NO YES hsa-miR-520d-3p YES NO YES hsa-miR-520e YES NO YES hsa-miR-542-3p YES YES YES hsa-miR-876-5p YES YES NO hsa-miR-93-5p YES YES NO Display: