ctcRbase

Entry Detail

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General Information

Database ID: SKCM04974 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: SREBF2 Full Name: sterol regulatory element binding transcription factor 2 Category: mRNA Synonyms: SREBP-2|SREBP2|bHLHd2 Chromosome: chr22 Strand: + Coordinate: Start Site(bp): 41833079 End Site(bp): 41907308 Gene Summary: This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] External Links: Ensembl ID: ENSG00000198911 HGNC ID: HGNC:11290 Entrez Gene: 6721

Expression Profile of SREBF2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p NO YES YES hsa-let-7b-5p NO YES YES hsa-let-7c-5p NO YES YES hsa-let-7d-5p NO YES YES hsa-let-7e-5p NO YES YES hsa-let-7f-5p NO YES YES hsa-let-7g-5p NO YES YES hsa-let-7i-5p NO YES YES hsa-miR-124-3p NO YES YES hsa-miR-125a-5p NO YES YES hsa-miR-125b-5p NO YES YES hsa-miR-185-5p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-365a-3p YES YES YES hsa-miR-532-3p YES NO YES hsa-miR-542-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-874-3p YES YES NO hsa-miR-98-5p NO YES YES Display: