ctcRbase

Entry Detail

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General Information

Database ID: SKCM05034 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MBTPS2 Full Name: membrane bound transcription factor peptidase, site 2 Category: mRNA Synonyms: BRESEK|IFAP|KFSD|KFSDX|OI19|OLMSX|S2P Chromosome: chrX Strand: + Coordinate: Start Site(bp): 21839636 End Site(bp): 21885424 Gene Summary: This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009] External Links: Ensembl ID: ENSG00000012174 HGNC ID: HGNC:15455 Entrez Gene: 51360

Expression Profile of MBTPS2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p NO YES YES hsa-let-7b-5p NO YES YES hsa-let-7c-5p NO YES YES hsa-let-7d-5p NO YES YES hsa-let-7e-5p NO YES YES hsa-let-7f-5p NO YES YES hsa-let-7g-5p NO YES YES hsa-let-7i-5p NO YES YES hsa-miR-101-3p NO YES YES hsa-miR-138-5p NO YES YES hsa-miR-141-3p NO YES YES hsa-miR-144-3p NO YES YES hsa-miR-181a-5p NO YES YES hsa-miR-181b-5p NO YES YES hsa-miR-181c-5p NO YES YES hsa-miR-181d-5p NO YES YES hsa-miR-200a-3p NO YES YES hsa-miR-204-5p NO YES YES hsa-miR-211-5p NO YES YES hsa-miR-24-3p NO YES YES hsa-miR-494-3p NO YES YES hsa-miR-98-5p NO YES YES Display: