Entry Detail



General Information

Database ID:SKCM05057
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:EXOC3
Full Name:exocyst complex component 3
Category:mRNA
Synonyms:SEC6|SEC6L1|Sec6p
Chromosome:chr5
Strand:+
Coordinate:
Start Site(bp):443158End Site(bp):471937
Gene Summary:The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000180104
HGNC ID:HGNC:30378
Entrez Gene:11336



Expression Profile of EXOC3 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-495-3p
YES
YES
NO
Display: