Entry Detail



General Information

Database ID:SKCM05059
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:NUP153
Full Name:nucleoporin 153
Category:mRNA
Synonyms:HNUP153|N153
Chromosome:chr6
Strand:-
Coordinate:
Start Site(bp):17615035End Site(bp):17706834
Gene Summary:Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm. The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain domain, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
External Links:
Ensembl ID:ENSG00000124789
HGNC ID:HGNC:8062
Entrez Gene:9972



Expression Profile of NUP153 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-124-3p
YES
YES
NO
hsa-miR-128-3p
YES
YES
NO
hsa-miR-129-5p
YES
YES
NO
hsa-miR-1297
YES
YES
YES
hsa-miR-133a-3p
YES
YES
YES
hsa-miR-133b
YES
YES
YES
hsa-miR-135a-5p
YES
YES
YES
hsa-miR-135b-5p
YES
YES
YES
hsa-miR-136-5p
YES
YES
NO
hsa-miR-140-3p
YES
NO
YES
hsa-miR-141-3p
YES
YES
NO
hsa-miR-183-5p
YES
YES
NO
hsa-miR-185-5p
YES
YES
NO
hsa-miR-197-3p
YES
YES
NO
hsa-miR-200a-3p
YES
YES
NO
hsa-miR-200b-3p
YES
YES
YES
hsa-miR-200c-3p
YES
YES
YES
hsa-miR-216a-5p
YES
YES
NO
hsa-miR-216b-5p
YES
YES
NO
hsa-miR-224-5p
YES
YES
YES
hsa-miR-26a-5p
YES
YES
YES
hsa-miR-26b-5p
YES
YES
YES
hsa-miR-27a-3p
YES
YES
YES
hsa-miR-27b-3p
YES
YES
YES
hsa-miR-31-5p
YES
YES
YES
hsa-miR-340-5p
YES
YES
NO
hsa-miR-361-5p
YES
YES
NO
hsa-miR-374a-5p
YES
YES
NO
hsa-miR-374b-5p
YES
YES
NO
hsa-miR-377-3p
YES
YES
YES
hsa-miR-383-5p
YES
YES
YES
hsa-miR-410-3p
YES
YES
NO
hsa-miR-421
YES
YES
NO
hsa-miR-429
YES
YES
YES
hsa-miR-455-3p
YES
NO
YES
hsa-miR-494-3p
YES
YES
NO
hsa-miR-495-3p
YES
YES
NO
hsa-miR-506-3p
YES
YES
NO
hsa-miR-876-5p
YES
YES
NO
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