| ncRNA Symbol: | TGFBI |
| Full Name: | transforming growth factor beta induced |
| Category: | mRNA |
| Synonyms: | BIGH3|CDB1|CDG2|CDGG1|CSD|CSD1|CSD2|CSD3|EBMD|LCD1 |
| Chromosome: | chr5 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 136028895 | End Site(bp): | 136063818 | |
| Gene Summary: | This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008] |
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