Entry Detail



General Information

Database ID:SKCM05084
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:TGFBI
Full Name:transforming growth factor beta induced
Category:mRNA
Synonyms:BIGH3|CDB1|CDG2|CDGG1|CSD|CSD1|CSD2|CSD3|EBMD|LCD1
Chromosome:chr5
Strand:+
Coordinate:
Start Site(bp):136028895End Site(bp):136063818
Gene Summary:This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000120708
HGNC ID:HGNC:11771
Entrez Gene:7045



Expression Profile of TGFBI Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-106b-5p
YES
YES
NO
hsa-miR-132-3p
YES
YES
NO
hsa-miR-17-5p
YES
YES
NO
hsa-miR-181a-5p
YES
YES
NO
hsa-miR-181b-5p
YES
YES
NO
hsa-miR-181c-5p
YES
YES
NO
hsa-miR-181d-5p
YES
YES
NO
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-212-3p
YES
YES
NO
hsa-miR-21-5p
YES
YES
YES
hsa-miR-22-3p
YES
YES
NO
hsa-miR-329-3p
YES
YES
YES
hsa-miR-34a-5p
YES
YES
NO
hsa-miR-34c-5p
YES
YES
NO
hsa-miR-362-3p
YES
YES
YES
hsa-miR-376a-3p
YES
YES
NO
hsa-miR-376b-3p
YES
YES
NO
hsa-miR-429
YES
YES
NO
hsa-miR-449a
YES
YES
NO
hsa-miR-449b-5p
YES
YES
NO
hsa-miR-485-5p
YES
YES
NO
hsa-miR-489-3p
YES
NO
YES
hsa-miR-519d-3p
YES
YES
NO
hsa-miR-543
YES
YES
NO
hsa-miR-590-5p
YES
YES
YES
hsa-miR-760
YES
NO
YES
hsa-miR-93-5p
YES
YES
NO
hsa-miR-9-5p
YES
YES
YES
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