Entry Detail



General Information

Database ID:SKCM05092
Cancer Type:melanoma
Dataset:GSE38495
CTCs/CTM Isolation Method:immunomagnetic purification



Gene Information

ncRNA Symbol:CLPX
Full Name:caseinolytic mitochondrial matrix peptidase chaperone subunit
Category:mRNA
Synonyms:EPP2
Chromosome:chr15
Strand:-
Coordinate:
Start Site(bp):65148219End Site(bp):65185342
Gene Summary:The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015]
External Links:
Ensembl ID:ENSG00000166855
HGNC ID:HGNC:2088
Entrez Gene:10845



Expression Profile of CLPX Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-139-5p
YES
YES
NO
hsa-miR-186-5p
YES
YES
NO
hsa-miR-194-5p
YES
YES
NO
hsa-miR-300
YES
YES
NO
hsa-miR-320a
YES
YES
NO
hsa-miR-320b
YES
YES
NO
hsa-miR-320c
YES
YES
NO
hsa-miR-320d
YES
YES
NO
hsa-miR-33a-5p
YES
YES
YES
hsa-miR-33b-5p
YES
YES
YES
hsa-miR-361-5p
YES
YES
NO
hsa-miR-381-3p
YES
YES
NO
hsa-miR-384
YES
YES
NO
hsa-miR-410-3p
YES
YES
NO
hsa-miR-532-5p
YES
NO
YES
hsa-miR-543
YES
YES
NO
hsa-miR-599
YES
YES
NO
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