ctcRbase

Entry Detail

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General Information

Database ID: SKCM05170 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ACTR1B Full Name: ARP1 actin related protein 1 homolog B Category: mRNA Synonyms: ARP1B|CTRN2|PC3 Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 97655963 End Site(bp): 97664107 Gene Summary: This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008] External Links: Ensembl ID: ENSG00000115073 HGNC ID: HGNC:168 Entrez Gene: 10120

Expression Profile of ACTR1B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-150-5p YES NO YES hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-451a YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-7-5p YES YES NO Display: