ctcRbase

Entry Detail

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General Information

Database ID: SKCM05175 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MYCBP2 Full Name: MYC binding protein 2, E3 ubiquitin protein ligase Category: mRNA Synonyms: Myc-bp2|PAM|Phr Chromosome: chr13 Strand: - Coordinate: Start Site(bp): 77044655 End Site(bp): 77327050 Gene Summary: This gene encodes an E3 ubiquitin-protein ligase and member of the PHR (Phr1/MYCBP2, highwire and RPM-1) family of proteins. The encoded protein plays a role in axon guidance and synapse formation in the developing nervous system. In mammalian cells, this protein regulates the cAMP and mTOR signaling pathways, and may additionally regulate autophagy. Reduced expression of this gene has been observed in acute lymphoblastic leukemia patients and a mutation in this gene has been identified in patients with a rare inherited vision defect. [provided by RefSeq, Mar 2017] External Links: Ensembl ID: ENSG00000005810 HGNC ID: HGNC:23386 Entrez Gene: 23077

Expression Profile of MYCBP2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES NO hsa-miR-129-5p YES YES YES hsa-miR-132-3p YES YES YES hsa-miR-137 YES YES NO hsa-miR-140-5p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-212-3p YES YES YES hsa-miR-22-3p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-27a-3p YES NO YES hsa-miR-27b-3p YES NO YES hsa-miR-300 YES YES YES hsa-miR-32-5p YES YES NO hsa-miR-338-3p YES YES YES hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-371a-5p YES YES YES hsa-miR-375 YES YES NO hsa-miR-381-3p YES YES YES hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-488-3p YES NO YES hsa-miR-489-3p YES NO YES hsa-miR-506-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: