ctcRbase

Entry Detail

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General Information

Database ID: SKCM05200 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: TJP2 Full Name: tight junction protein 2 Category: mRNA Synonyms: C9DUPq21.11|DFNA51|DUP9q21.11|PFIC4|X104|ZO2 Chromosome: chr9 Strand: + Coordinate: Start Site(bp): 69121264 End Site(bp): 69255208 Gene Summary: This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] External Links: Ensembl ID: ENSG00000119139 HGNC ID: HGNC:11828 Entrez Gene: 9414

Expression Profile of TJP2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-128-3p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-132-3p YES YES NO hsa-miR-137 YES YES NO hsa-miR-138-5p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-194-5p YES YES NO hsa-miR-212-3p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-342-3p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-506-3p YES YES NO Display: