ctcRbase

Entry Detail

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General Information

Database ID: SKCM05201 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MRPL28 Full Name: mitochondrial ribosomal protein L28 Category: mRNA Synonyms: MAAT1|p15 Chromosome: chr16 Strand: - Coordinate: Start Site(bp): 367384 End Site(bp): 370527 Gene Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000086504 HGNC ID: HGNC:14484 Entrez Gene: 10573

Expression Profile of MRPL28 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO Display: