ctcRbase

Entry Detail

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General Information

Database ID: SKCM05212 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: MBD4 Full Name: methyl-CpG binding domain 4, DNA glycosylase Category: mRNA Synonyms: MED1 Chromosome: chr3 Strand: - Coordinate: Start Site(bp): 129430944 End Site(bp): 129440179 Gene Summary: The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013] External Links: Ensembl ID: ENSG00000129071 HGNC ID: HGNC:6919 Entrez Gene: 8930

Expression Profile of MBD4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-219a-5p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-320a NO YES NO hsa-miR-320b NO YES NO hsa-miR-320c NO YES NO hsa-miR-320d NO YES NO hsa-miR-329-3p YES NO NO hsa-miR-433-3p NO YES YES hsa-miR-454-3p YES YES NO hsa-miR-96-5p YES YES NO Display: