ctcRbase

Entry Detail

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General Information

Database ID: SKCM05234 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: NFS1 Full Name: NFS1, cysteine desulfurase Category: mRNA Synonyms: HUSSY-08|IscS|NIFS Chromosome: chr20 Strand: - Coordinate: Start Site(bp): 35668055 End Site(bp): 35699359 Gene Summary: Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010] External Links: Ensembl ID: ENSG00000244005 HGNC ID: HGNC:15910 Entrez Gene: 9054

Expression Profile of NFS1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES NO NO hsa-miR-107 YES NO NO hsa-miR-136-5p YES YES NO hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-214-3p YES NO NO hsa-miR-335-5p YES YES NO hsa-miR-424-5p YES YES YES hsa-miR-455-5p YES YES NO hsa-miR-497-5p YES YES YES Display: