ctcRbase

Entry Detail

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General Information

Database ID: SKCM05240 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: CD74 Full Name: CD74 molecule Category: mRNA Synonyms: DHLAG|HLADG|II|Ia-GAMMA|p33 Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 150401637 End Site(bp): 150412929 Gene Summary: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] External Links: Ensembl ID: ENSG00000019582 HGNC ID: HGNC:1697 Entrez Gene: 972

Expression Profile of CD74 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-24-3p YES YES NO hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-328-3p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-653-5p YES YES NO hsa-miR-873-5p YES YES NO Display: