ctcRbase

Entry Detail

---



General Information

Database ID: SKCM05258 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: ACTA2 Full Name: actin, alpha 2, smooth muscle, aorta Category: mRNA Synonyms: ACTSA Chromosome: chr10 Strand: - Coordinate: Start Site(bp): 88935074 End Site(bp): 88991339 Gene Summary: This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017] External Links: Ensembl ID: ENSG00000107796 HGNC ID: HGNC:130 Entrez Gene: 59

Expression Profile of ACTA2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p YES NO YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-206 YES YES NO hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-376c-3p YES YES NO hsa-miR-9-5p YES YES NO Display: