ctcRbase

Entry Detail

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General Information

Database ID: SKCM05261 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: THEM4 Full Name: thioesterase superfamily member 4 Category: mRNA Synonyms: CTMP Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 151873584 End Site(bp): 151909808 Gene Summary: Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000159445 HGNC ID: HGNC:17947 Entrez Gene: 117145

Expression Profile of THEM4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-128-3p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-375 YES YES NO hsa-miR-448 YES YES NO hsa-miR-496 YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-7-5p YES YES NO hsa-miR-875-5p YES YES NO hsa-miR-93-5p YES YES NO Display: