| ncRNA Symbol: | PILRB |
| Full Name: | paired immunoglobin-like type 2 receptor beta |
| Category: | mRNA |
| Synonyms: | FDFACT1|FDFACT2 |
| Chromosome: | chr7 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 100352176 | End Site(bp): | 100367733 |
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| Gene Summary: | The paired immunoglobin-like type 2 receptors consist of highly related activating and inhibitory receptors that are involved in the regulation of many aspects of the immune system. The paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This gene encodes the activating member of the receptor pair and contains a truncated cytoplasmic tail relative to its inhibitory counterpart (PILRA), that has a long cytoplasmic tail with immunoreceptor tyrosine-based inhibitory (ITIM) motifs. This gene is thought to have arisen from a duplication of the inhibitory PILRA gene and evolved to acquire its activating function. [provided by RefSeq, Jun 2013] |
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