ctcRbase

Entry Detail

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General Information

Database ID: SKCM05277 Cancer Type: melanoma Dataset: GSE38495 CTCs/CTM Isolation Method: immunomagnetic purification

Gene Information

ncRNA Symbol: RBM5 Full Name: RNA binding motif protein 5 Category: mRNA Synonyms: G15|H37|LUCA-15|LUCA15|RMB5 Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 50088908 End Site(bp): 50119021 Gene Summary: This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer. [provided by RefSeq, Oct 2011] External Links: Ensembl ID: ENSG00000003756 HGNC ID: HGNC:9902 Entrez Gene: 10181

Expression Profile of RBM5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1-3p YES YES NO hsa-miR-140-5p YES YES NO hsa-miR-182-5p YES YES YES hsa-miR-206 YES YES NO hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-28-5p YES YES NO hsa-miR-300 YES YES NO hsa-miR-30a-5p YES YES NO hsa-miR-30b-5p YES YES NO hsa-miR-30c-5p YES YES NO hsa-miR-30d-5p YES YES NO hsa-miR-30e-5p YES YES NO hsa-miR-323a-3p YES NO YES hsa-miR-371a-5p YES YES NO hsa-miR-613 YES YES NO hsa-miR-96-5p YES YES NO Display: